製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to BHLHA15
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide corresponding to C terminal amino acids 167-197 of Human BHLHA15 (NP_803238.1), conjugated to KLH.

  • ポジティブ・コントロール
    • U251 cell line lysates; Mouse Neuro-2a cell line lysates

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab107390 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 21 kDa.

ターゲット情報

  • 機能
    Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'.
  • 組織特異性
    Expressed in brain, liver, spleen and skeletal muscle.
  • 配列類似性
    Contains 1 basic helix-loop-helix (bHLH) domain.
  • ドメイン
    Lacks a classic transcription activation domain and instead possesses an N-terminal region capable of inhibiting heterologous activators.
  • 細胞内局在
    Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Basic helix loop helix domain containing class B 8 antibody
    • Basic helix loop helix family member a15 antibody
    • BHA15_HUMAN antibody
    • Bhlha15 antibody
    • bHLHB8 antibody
    • Class A basic helix-loop-helix protein 15 antibody
    • Class B basic helix-loop-helix protein 8 antibody
    • Class II bHLH protein MIST1 antibody
    • intestine and stomach expression 1 antibody
    • MIST 1 antibody
    • MIST-1 antibody
    • MIST1 antibody
    • Muscle antibody
    • Muscle intestine and stomach expression 1 antibody
    • protein MIST1 antibody
    see all

画像

  • Anti-BHLHA15 antibody (ab107390) at 1/100 dilution + U251 cell line lysates at 35 µg

    Predicted band size : 21 kDa
  • Anti-BHLHA15 antibody (ab107390) at 1/100 dilution + Mouse Neuro-2a cell line lysates at 35 µg

    Predicted band size : 21 kDa

プロトコール

参考文献

ab107390 has not yet been referenced specifically in any publications.

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