製品の概要
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製品名Anti-BHLHA15 antibody [6E8/A12/C11P1]
BHLHA15 一次抗体 製品一覧 -
製品の詳細Mouse monoclonal [6E8/A12/C11P1] to BHLHA15
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由来種Mouse
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アプリケーション適用あり: WB, IHC-P, IHC-Frmore details
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種交差性交差種: Mouse, Human
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免疫原
Synthetic peptide, corresponding to C terminal amino acids 175-197 of Mouse BHLHA15.
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ポジティブ･コントロール
- Mouse pancreas tissue.
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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バッファーPreservative: 0.05% Sodium azide
Constituents: 99.85% PBS, 0.1% BSA -
Concentration information loading... -
精製度Protein A purified
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ポリ/モノモノクローナル
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クローン名6E8/A12/C11P1
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab110919 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | 1/250. Predicted molecular weight: 21 kDa. | |
| IHC-P | 1/50. | |
| IHC-Fr | Use at an assay dependent dilution. |
ターゲット情報
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機能Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'.
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組織特異性Expressed in brain, liver, spleen and skeletal muscle.
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配列類似性Contains 1 basic helix-loop-helix (bHLH) domain.
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ドメインLacks a classic transcription activation domain and instead possesses an N-terminal region capable of inhibiting heterologous activators.
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細胞内局在Nucleus.
- Information by UniProt
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参照データベース
- Entrez Gene: 168620 Human
- Entrez Gene: 17341 Mouse
- Omim: 608606 Human
- SwissProt: Q7RTS1 Human
- SwissProt: Q9QYC3 Mouse
- Unigene: 674510 Human
- Unigene: 386767 Mouse
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別名
- Basic helix loop helix domain containing class B 8 antibody
- Basic helix loop helix family member a15 antibody
- BHA15_HUMAN antibody
see all
画像
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![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BHLHA15 antibody [6E8/A12/C11P1] (ab110919)](http://a.abcam.com/ps/products/110/ab110919/Images/BHLHA15-Primary-antibodies-ab110919-1.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BHLHA15 antibody [6E8/A12/C11P1] (ab110919)ab110919 staining BHLHA15 in paraffin-embedded Mouse pancreas tissue by Immunohistochemistry. Note: nuclear staining in acinar cells but not in duct or islet cells.
参考文献
ab110919 has not yet been referenced specifically in any publications.
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"