製品の概要

  • 製品名Anti-BFSP2 antibody
    BFSP2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to BFSP2
  • アプリケーション適用あり: IHC-P, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    antigen sequence: LSRNYEEDVK LLHKQLAGCE LEQMDAPIGT GLDDILETIR IQWERDVEKN RVEAGALLQA KQQAEVAHMS QTQEEKLAAA LRVE, corresponding to internal sequence amino acids 237-320 of Human BFSP2.

  • ポジティブ・コントロール
    • Human lateral ventricle tissue; A 431 cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab122476 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/2500 - 1/5000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml. using PFA/Triton X-100 Fixation/Permeabilization.

ターゲット情報

  • 機能Involved in stabilization of lens fiber cell cytoskeleton.
  • 組織特異性Lens.
  • 関連疾患Defects in BFSP2 are the cause of cataract autosomal dominant BFSP2-related (ADC-BFSP2) [MIM:611597]; also known as cataract autosomal dominant multiple types 1. Cataract is an opacification of the crystalline lens of the eye that frequently results in visual impairment or blindness. Opacities vary in morphology, are often confined to a portion of the lens, and may be static or progressive. In general, the more posteriorly located and dense an opacity, the greater the impact on visual function. Cataract autosomal dominant BFSP2-related is characterized by a variable phenotype that may or may not be consistent within a family. The opacities can be nuclear, sutural, stellate cortical, lamellar, cortical, nuclear embryonic, Y-sutural, punctate cortical, congenital or with juvenile- and adult-onset.
  • 配列類似性Belongs to the intermediate filament family.
  • 細胞内局在Membrane. Cytoplasm. Cytoplasm > cytoskeleton. Membrane- and cytoskeleton-associated.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 49 kDa cytoskeletal protein antibody
    • Beaded filament protein CP49 antibody
    • Beaded filament structural protein 2 antibody
    • Beaded filament structural protein 2, phakinin antibody
    • Bfps2, Cytoskeletal protein, 49 kD antibody
    • BFSP2 antibody
    • BFSP2_HUMAN antibody
    • CP47 antibody
    • CP49 antibody
    • Lens fiber cell beaded filament protein CP 47 antibody
    • Lens fiber cell beaded filament protein CP 49 antibody
    • Lens intermediate filament-like light antibody
    • LIFL-L antibody
    • MGC142078 antibody
    • MGC142080 antibody
    • Phakinin antibody
    • PHAKOSIN antibody
    see all

Anti-BFSP2 antibody 画像

  • ab122476 staining BFSP2 in paraffin-embedded Human lateral ventricle tissue by Immunohistochemistry.
  • ab122476 at 4 µg/ml staining BFSP2 in PFA/Triton X-100 fixed/permeabilized A431 cells by Immunofluorescence (green).

Anti-BFSP2 antibody (ab122476) 使用論文

ab122476 has not yet been referenced specifically in any publications.

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