Anti-beta Synuclein 抗体, prediluted (ab15533)

製品の概要

  • 製品名
    Anti-beta Synuclein antibody, prediluted
    beta Synuclein 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to beta Synuclein, prediluted
  • 由来種
    Rabbit
  • 特異性
    This antibody is specific for beta synuclein and does not cross react with alpha or gamma synuclein. Stains neuronal cytosol and presynaptic terminals.
  • アプリケーション
    適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rat
  • 免疫原

    Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Human) (C terminal).

  • ポジティブ・コントロール
    • Brain.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab15533 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報
    IHC-P: Ready to use for 10 minutes at room temperature. No special pretreatment is required for the immunohistochemical staining of formalin/paraffin tissues.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.
    • 組織特異性
      Expressed predominantly in brain; concentrated in presynaptic nerve terminals.
    • 配列類似性
      Belongs to the synuclein family.
    • 翻訳後修飾
      Phosphorylated. Phosphorylation by G-protein coupled receptor kinases (GRK) is more efficient than phosphorylation by CK1, CK2 and CaM-kinase II.
    • 細胞内局在
      Cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 14 kDa brain-specific protein antibody
      • Beta-synuclein antibody
      • Phosphoneuroprotein 14 antibody
      • PNP14 antibody
      • Sncb antibody
      • Synuclein beta antibody
      • SYUB_HUMAN antibody
      see all

    画像

    • ab15533 staining beta Synuclein in human brain by Immunohistochemistry (FFPE-sections).

    参考文献

    ab15533 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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