Anti-beta Synuclein 抗体 (ab6164)

製品の概要

  • 製品名Anti-beta Synuclein antibody
    beta Synuclein 一次抗体 製品一覧
  • 製品の詳細
    Sheep polyclonal to beta Synuclein
  • 特異性Cross reactivity: This antibody is known to react with rat and human and other rodents. Cross reactivity with other species has not been tested yet.
  • アプリケーション適用あり: IHC-P, IHC-Frmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide IEPLMEPEGESYEDPPQE corresponds to the carboxy terminal sequence of human beta-synuclein (108-125) and coupled to diphtheria toxoid via a cysteine residue attached to the C- terminal. The conjugate was cross-linked by maleimidocaproyl-N-hydroxy succinimide.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab6164 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
IHC-Fr
  • 追加情報Immunohistochemistry: 1 ug/ml
    Western Blot: Not tested.
    Immunoblot: Not tested.
    1 site ELISA: Not tested.
    Biological Inhibition: Not tested.
  • ターゲット情報

    • 機能Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.
    • 組織特異性Expressed predominantly in brain; concentrated in presynaptic nerve terminals.
    • 配列類似性Belongs to the synuclein family.
    • 翻訳後修飾Phosphorylated. Phosphorylation by G-protein coupled receptor kinases (GRK) is more efficient than phosphorylation by CK1, CK2 and CaM-kinase II.
    • 細胞内局在Cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 14 kDa brain-specific protein antibody
      • Beta-synuclein antibody
      • Phosphoneuroprotein 14 antibody
      • PNP14 antibody
      • Sncb antibody
      • Synuclein beta antibody
      • SYUB_HUMAN antibody
      see all

    Anti-beta Synuclein antibody (ab6164) 使用論文

    ab6164 has not yet been referenced specifically in any publications.

    Product Wall

    Ab6164 is stored in 5mM Tris-HCl, 0.9% NaCl. Please contact us again if you have any additional questions.

    All of the information we have for each of the anti-human-synuclein antibodies in our catalog is on the online datasheets. We are not aware of studies where they might have been used to detect relative levels of synuclein expression in leukocytes.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"