製品の概要

  • 製品名Anti-beta Synuclein antibody
    beta Synuclein 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to beta Synuclein
  • 特異性ab53167 detects endogenous levels of total beta Synuclein protein.
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    A synthetic peptide derived from human beta Synuclein.

  • ポジティブ・コントロール
    • HeLa cell extracts.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab53167 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 14 kDa (predicted molecular weight: 14 kDa).
ELISA 1/5000.

ターゲット情報

  • 機能Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.
  • 組織特異性Expressed predominantly in brain; concentrated in presynaptic nerve terminals.
  • 配列類似性Belongs to the synuclein family.
  • 翻訳後修飾Phosphorylated. Phosphorylation by G-protein coupled receptor kinases (GRK) is more efficient than phosphorylation by CK1, CK2 and CaM-kinase II.
  • 細胞内局在Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 14 kDa brain-specific protein antibody
    • Beta-synuclein antibody
    • Phosphoneuroprotein 14 antibody
    • PNP14 antibody
    • Sncb antibody
    • Synuclein beta antibody
    • SYUB_HUMAN antibody
    see all

Anti-beta Synuclein antibody 画像

  • All lanes : Anti-beta Synuclein antibody (ab53167) at 1/500 dilution

    Lane 1 : HeLa cell extract
    Lane 2 : HeLa cell extract with immunising peptide


    Predicted band size : 14 kDa
    Observed band size : 14 kDa

Anti-beta Synuclein antibody (ab53167) 使用論文

ab53167 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"