beta-Nicotinamide adenine dinucleotide (beta-NAD), P2Y11 agonist. (ab120403)
Key features and details
- Coenzyme and enzyme substrate. P2Y11 agonist.
- CAS Number: 53-84-9
- Soluble in water to 50 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
beta-Nicotinamide adenine dinucleotide (beta-NAD), P2Y11 agonist. -
製品の詳細
Coenzyme and enzyme substrate. P2Y11 agonist. -
別名
- β-NAD
- NAD
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生理活性の詳細
Major electron acceptor molecule in biological oxidations. Acts as a coenzyme for hydride-transfer enzymes and a substrate for NAD(+)-consuming enzymes, which include ADP-ribose transferases, poly(ADP-ribose) polymerases, cADP-ribose synthases and sirtuins. Recently reported to be a P2Y11 agonist.
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CAS 番号
53-84-9 -
構造式
製品の特性
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体系名
Diphosphoric acid-1-adenosin-5'-yl ester-2-[(1S)-1-(3-carbamoylpyridinio)-D-1,4-anhydroribitol-5-yl ester]betaine -
分子量
663.43 -
分子式
C21H27N7O14P2 -
PubChem 登録番号
5892 -
保存方法
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in water to 50 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)(O)OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N -
由来
Synthetic
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研究分野
画像
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (1)
ab120403 は 1 報の論文で使用されています。
- Echeverri Tirado LC et al. PARP-1 Is Critical for Recruitment of Dendritic Cells to the Lung in a Mouse Model of Asthma but Dispensable for Their Differentiation and Function. Mediators Inflamm 2019:1656484 (2019). PubMed: 31178661