Anti-beta Endorphin 抗体 [B 31.15] (ab54205)
Key features and details
- Mouse monoclonal [B 31.15] to beta Endorphin
- Suitable for: IHC-Fr, IHC-P
- Reacts with: Rat, Human, Macaque monkey
- Isotype: IgG1
製品の概要
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製品名
Anti-beta Endorphin antibody [B 31.15] -
製品の詳細
Mouse monoclonal [B 31.15] to beta Endorphin -
由来種
Mouse -
アプリケーション
適用あり: IHC-Fr, IHC-Pmore details -
種交差性
交差種: Rat, Human, Macaque monkey -
免疫原
Full length native human beta Endorphin.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.20
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
B 31.15 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab54205の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-Fr |
Use at an assay dependent concentration.
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IHC-P |
Use at an assay dependent concentration.
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特記事項 |
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IHC-Fr
Use at an assay dependent concentration. |
IHC-P
Use at an assay dependent concentration. |
ターゲット情報
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関連性
Beta-endorphin is an endogenous opioid peptide neurotransmitter found in the neurons of both the central and peripheral nervous system. ß-endorphin is a peptide, 31 amino acids long, resulting from processing of the precursor pro-opiomelanocortin (POMC). ß-endorphin is found in neurons of the hypothalamus as well as the pituitary gland. It is an agonist of the opioid receptors, with evidence suggesting that it serves as the endogenous ligand of the µ-opioid receptor, the same receptor to which the chemicals extracted from opium, such as morphine and codeine, have their analgesic and addictive effects -
細胞内局在
Secreted -
参照データベース
- Entrez Gene: 5443 Human
- Entrez Gene: 24664 Rat
- Omim: 176830 Human
- SwissProt: P01189 Human
- SwissProt: P01194 Rat
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別名
- Beta endorphin antibody
- Corticotropin lipotropin antibody
- POMC antibody
- Proopiomelanocortin antibody
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab54205 は 4 報の論文で使用されています。
- Lau BK et al. Mu-Opioids Suppress GABAergic Synaptic Transmission onto Orbitofrontal Cortex Pyramidal Neurons with Subregional Selectivity. J Neurosci 40:5894-5907 (2020). PubMed: 32601247
- Dees WL et al. Regulation of prepubertal dynorphin secretion in the medial basal hypothalamus of the female rat. J Neuroendocrinol 31:e12810 (2019). PubMed: 31715027
- Ranganathan S et al. Molecular interpretation of ACTH-ß-endorphin coaggregation: relevance to secretory granule biogenesis. PLoS One 7:e31924 (2012). IHC-Fr ; Rat . PubMed: 22403619
- Ubuka T et al. Gonadotropin-inhibitory hormone identification, cDNA cloning, and distribution in rhesus macaque brain. J Comp Neurol 517:841-55 (2009). ICC/IF ; Macaque monkey . PubMed: 19844991