Anti-beta amyloid 1-43 抗体 [9C4] (ab22258)

製品の概要

  • 製品名Anti-beta amyloid 1-43 antibody [9C4]
  • 製品の詳細
    Mouse monoclonal [9C4] to beta amyloid 1-43
  • 特異性Reactive to the c-terminus of beta amyloid and specific for the isoform ending at the 43rd amino acid.
  • アプリケーション適用あり: WB, ELISA, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide corresponding to Human beta amyloid 1-43 (C terminal).

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: PBS
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノモノクローナル
  • クローン名9C4
  • ミエローマunknown
  • アイソタイプIgG1
  • 軽鎖の種類unknown
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab22258 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/1000. Predicted molecular weight: 87 kDa.
ELISA 1/500.
IHC-P Use at an assay dependent concentration. Retrieve antigens with 70% Formic acid for 10-30 minutes at room temperature before commencing with IHC staining protocol.

ターゲット情報

  • 関連性The cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides. beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last Amyloid precursor protein processing step. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides are major constituents of the plaques and tangles that occur in Alzheimer's disease. beta Amyloid antibodies and peptides have been developed as tools for elucidating the biology of Alzheimer's disease.
  • 細胞内局在Plasma membrane
  • 参照データベース
  • 別名
    • ABPP antibody
    • APPI antibody
    • CVAP antibody
    • PN-II antibody
    • PreA4 antibody
    • Protease nexin-II antibody
    see all

Anti-beta amyloid 1-43 antibody [9C4] (ab22258) 使用論文

ab22258 has not yet been referenced specifically in any publications.

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