製品の概要

  • 製品名
    Anti-beta Actin antibody
    beta Actin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to beta Actin
  • 由来種
    Rabbit
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to amino acids at the C-terminal of Human beta Actin.

  • ポジティブ･コントロール
    • HeLa, 293T, PC12 and NIH3T3 cell lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab119716 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/5000. Predicted molecular weight: 42 kDa.

ターゲット情報

  • 機能
    Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
  • 関連疾患
    Defects in ACTB are a cause of dystonia juvenile-onset (DYTJ) [MIM:607371]. DYTJ is a form of dystonia with juvenile onset. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. DYTJ patients manifest progressive, generalized, dopa-unresponsive dystonia, developmental malformations and sensory hearing loss.
  • 配列類似性
    Belongs to the actin family.
  • 翻訳後修飾
    ISGylated.
  • 細胞内局在
    Cytoplasm > cytoskeleton. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
  • Information by UniProt
  • 参照データベース
    see all
  • 別名
    • A26C1A antibody
    • A26C1B antibody
    • ACTB antibody
    • ACTB_HUMAN antibody
    • Actin beta antibody
    • Actin cytoplasmic 1 antibody
    • Actin, cytoplasmic 1, N-terminally processed antibody
    • Actx antibody
    • b actin antibody
    • Beta cytoskeletal actin antibody
    • Beta-actin antibody
    • BRWS1 antibody
    • E430023M04Rik antibody
    • MGC128179 antibody
    • PS1TP5 binding protein 1 antibody
    • PS1TP5BP1 antibody
    see all

画像

  • Western blot - Anti-beta Actin antibody (ab119716)
    Western blot - Anti-beta Actin antibody (ab119716)
    All lanes : Anti-beta Actin antibody (ab119716) at 1/5000 dilution

    Lane 1 : HeLa cell lysate
    Lane 2 : 293T cell lysate
    Lane 3 : PC12 cell lysate
    Lane 4 : NIH3T3 cell lysate

    Predicted band size: 42 kDa

プロトコール

参考文献

This product has been referenced in:
  • Ma X  et al. Hippo signaling promotes JNK-dependent cell migration. Proc Natl Acad Sci U S A 114:1934-1939 (2017). Read more (PubMed: 28174264) »
  • Guo L  et al. Identification of Novel Epitopes with Agonistic Activity for the Development of Tumor Immunotherapy Targeting TRAIL-R1. J Cancer 8:2542-2553 (2017). Read more (PubMed: 28900492) »

See all 11 Publications for this product

ab119716 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

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