製品の概要

  • 製品名
    Anti-beta 4 Defensin antibody
    beta 4 Defensin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to beta 4 Defensin
  • アプリケーション
    適用あり: WB, Indirect ELISA, Sandwich ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Highly pure (>98%) human recombinant full length beta 4 Defensin

製品の特性

  • 製品の状態
    Lyophilised:Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.5 mg/ml. Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary.
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: None
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab70215 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 8 kDa.
Indirect ELISA Use a concentration of 0.5 - 2 µg/ml. Can be paired for ELISA with Rabbit polyclonal to beta 4 Defensin (Biotin) (ab70216).
Sandwich ELISA Use a concentration of 0.5 - 2 µg/ml. Can be paired for Sandwich ELISA with Rabbit polyclonal to beta 4 Defensin (Biotin) (ab70216). Capture

ターゲット情報

  • 機能
    Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103.
  • 組織特異性
    High expression in the testis. Gastric antrum exhibited relatively high levels. A lower expression is observed in uterus and neutrophils thyroid gland, lung, and kidney. No detectable expression in other tissues tested.
  • 配列類似性
    Belongs to the beta-defensin family.
  • 細胞内局在
    Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BD 4 antibody
    • BD-4 antibody
    • BD4 antibody
    • beta 104 antibody
    • Beta defensin 4 antibody
    • Beta-defensin 104 antibody
    • Beta-defensin 4 antibody
    • D104A_HUMAN antibody
    • DEFB-4 antibody
    • DEFB104B antibody
    • Defensin antibody
    • Defensin beta 104 antibody
    • Defensin beta 4 precursor antibody
    • hBD 4 antibody
    • hBD-4 antibody
    • hBD4 antibody
    see all

画像

  • ab70215 staining beta 40Defensin in the A549 cell line from Human Lung by ICC/IF (Immunocytochemistry/immunofluorescence) treated with cigarette smoke extract. Cells were fixed , permeabilized and blocked. Samples were incubated with primary antibody (1/500) for 1 hour. An Alexa Fluor®488-conjugated was used as the secondary antibody and DAPI used to stain the nuclei.

プロトコール

参考文献

This product has been referenced in:
  • Pierson T  et al. Cigarette smoke extract induces differential expression levels of beta-defensin peptides in human alveolar epithelial cells. Tob Induc Dis 11:10 (2013). ICC/IF ; Human . Read more (PubMed: 23627872) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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