Anti-beta 2 Microglobulin 抗体 (ab98327)

製品の概要

  • 製品名Anti-beta 2 Microglobulin antibody
    beta 2 Microglobulin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to beta 2 Microglobulin
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Guinea pig, Cat, Dog, African Green Monkey, Spider Monkey
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 1-50 (MSRSVALAVL ALLSLSGLEA IQRTPKIQVY SRHPAENGKS NFLNCYVSGF) of Human beta 2 Microglobulin (NP_004039).

  • ポジティブ・コントロール
    • Fetal thymus lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab98327 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 14 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
  • 関連疾患Defects in B2M are the cause of hypercatabolic hypoproteinemia (HYCATHYP) [MIM:241600]. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation.
    Note=Beta-2-microglobulin may adopt the fibrillar configuration of amyloid in certain pathologic states. The capacity to assemble into amyloid fibrils is concentration dependent. Persistently high beta(2)-microglobulin serum levels lead to amyloidosis in patients on long-term hemodialysis.
  • 配列類似性Belongs to the beta-2-microglobulin family.
    Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
  • 翻訳後修飾Glycation of Ile-21 is observed in long-term hemodialysis patients.
  • 細胞内局在Secreted. Detected in serum and urine.
  • Information by UniProt
  • 参照データベース
  • 別名
    • B2M antibody
    • B2MG_HUMAN antibody
    • Beta 2 microglobin antibody
    • Beta 2 microglobulin antibody
    • Beta 2 microglobulin precursor antibody
    • Beta chain of mhc class 1 proteins antibody
    • Beta chain of MHC class I molecules antibody
    • Beta-2-microglobulin form pI 5.3 antibody
    • CDABP0092 antibody
    • Hdcma22p antibody
    see all

Anti-beta 2 Microglobulin antibody 画像

  • Anti-beta 2 Microglobulin antibody (ab98327) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal thymus lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 14 kDa

Anti-beta 2 Microglobulin antibody (ab98327) 使用論文

ab98327 has not yet been referenced specifically in any publications.

Product Wall

In review of the immunogen sequence used for creating ab75853 I see this sequence share only 69.2% identity with rabbit beta-2-microglobulin. Generally we do not expect reactivity below 80%. Overall I have found that the sequence homologies of human...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"