製品の概要

  • 製品名
    Anti-beta 2 Microglobulin antibody
    beta 2 Microglobulin 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to beta 2 Microglobulin
  • アプリケーション
    適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-120 of Human beta 2 Microglobulin

  • 特記事項

    Abcam is committed to meeting high standards of ethical manufacturing and has decided to discontinue this product by June 2019 as it has been generated by the ascites method. We are sorry for any inconvenience this may cause. We would recommend antibody ab175031 as a replacement.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab54810 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
IHC-P
  • 追加情報
    WB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
    • 関連疾患
      Defects in B2M are the cause of hypercatabolic hypoproteinemia (HYCATHYP) [MIM:241600]. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation.
      Note=Beta-2-microglobulin may adopt the fibrillar configuration of amyloid in certain pathologic states. The capacity to assemble into amyloid fibrils is concentration dependent. Persistently high beta(2)-microglobulin serum levels lead to amyloidosis in patients on long-term hemodialysis.
    • 配列類似性
      Belongs to the beta-2-microglobulin family.
      Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
    • 翻訳後修飾
      Glycation of Ile-21 is observed in long-term hemodialysis patients.
    • 細胞内局在
      Secreted. Detected in serum and urine.
    • Information by UniProt
    • 参照データベース
    • 別名
      • B2M antibody
      • B2MG_HUMAN antibody
      • Beta 2 microglobin antibody
      • Beta 2 microglobulin antibody
      • Beta 2 microglobulin precursor antibody
      • Beta chain of mhc class 1 proteins antibody
      • Beta chain of MHC class I molecules antibody
      • Beta-2-microglobulin form pI 5.3 antibody
      • CDABP0092 antibody
      • Hdcma22p antibody
      • IMD43 antibody
      see all

    画像

    • beta 2 Microglobulin antibody (ab54810) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human esophagus.


    • Predicted band size : 14 kDa
      beta 2 Microglobulin antibody (ab54810) at 1ug/lane + U-2 cell lysate at 25ug/lane.

    参考文献

    ab54810 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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