Anti-BCRP/ABCG2 抗体 - Carboxyterminal end (ab64757)

製品の概要

  • 製品名Anti-BCRP/ABCG2 antibody - Carboxyterminal end
    BCRP/ABCG2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to BCRP/ABCG2 - Carboxyterminal end
  • 特異性This antibody reacts with BCRP/ABCG2
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    This information is considered to be commercially sensitive

  • ポジティブ・コントロール
    • HepG2 cell line lysates

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab64757 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/50 - 1/100. Detects a band of approximately 72 kDa (predicted molecular weight: 72 kDa).
ELISA 1/1000.

ターゲット情報

  • 機能Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
  • 組織特異性Highly expressed in placenta. Low expression in small intestine, liver and colon.
  • 配列類似性Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
    Contains 1 ABC transmembrane type-2 domain.
    Contains 1 ABC transporter domain.
  • 翻訳後修飾Glycosylation-deficient ABCG2 is normally expressed and functional.
  • 細胞内局在Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ABC transporter antibody
    • ABC15 antibody
    • ABCG 2 antibody
    • ABCG2 antibody
    • ABCG2_HUMAN antibody
    • ABCP antibody
    • ATP binding cassette sub family G (WHITE) member 2 antibody
    • ATP binding cassette transporter G2 antibody
    • ATP-binding cassette sub-family G member 2 antibody
    • BCRP antibody
    • BCRP1 antibody
    • BMDP antibody
    • Breast cancer resistance protein antibody
    • CD338 antibody
    • CDw338 antibody
    • CDw338 antigen antibody
    • EST157481 antibody
    • GOUT1 antibody
    • MGC102821 antibody
    • Mitoxantrone resistance associated protein antibody
    • Mitoxantrone resistance-associated protein antibody
    • MRX antibody
    • Multi drug resistance efflux transport ATP binding cassette sub family G (WHITE) member 2 antibody
    • MXR antibody
    • MXR1 antibody
    • Placenta specific ATP binding cassette transporter antibody
    • Placenta specific MDR protein antibody
    • Placenta-specific ATP-binding cassette transporter antibody
    • UAQTL1 antibody
    see all

Anti-BCRP/ABCG2 antibody - Carboxyterminal end 画像

  • Anti-BCRP/ABCG2 antibody - Carboxyterminal end (ab64757) at 1/60 dilution + HepG2 cell line lysates at 35 µg

    Predicted band size : 72 kDa
    Observed band size : 72 kDa

Anti-BCRP/ABCG2 antibody - Carboxyterminal end (ab64757) 使用論文

ab64757 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"