製品の概要

  • 製品名Anti-BCMO1 antibody
    BCMO1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to BCMO1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region btween internal sequence amino acids 270-300 of Human BCMO1 (NP_059125.2).

  • ポジティブ・コントロール
    • WiDr cell line lysates

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab107418 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 63 kDa.

ターゲット情報

  • 機能Symmetrically cleaves beta-carotene into two molecules of retinal. The reaction proceeds in three stages, epoxidation of the 15,15'-double bond, hydration of the double bond leading to ring opening, and oxidative cleavage of the diol formed.
  • 組織特異性Highly expressed in retinal pigment epithelium. Also expressed in kidney, testis, liver, brain, small intestine and colon.
  • パスウェイCofactor metabolism; retinol metabolism.
  • 関連疾患Defects in BCMO1 are the cause of autosomal dominant hypercarotenemia and vitamin A deficiency (ADHVAD) [MIM:115300]. Vitamin A is essential for normal embryonic development as well as normal physiological functions in children and adults. Hypercarotenemia is characterized by an excess carotene in the serum, but unlike excess vitamin A, carotene is non-toxic. So far, only a few cases of excess vitamin A have been reported. Individuals were thought to be vitamin A deficient due to an impairment in the conversion of carotenoids to retinal in the intestine.
  • 配列類似性Belongs to the carotenoid oxygenase family.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BCDO antibody
    • BCDO1 antibody
    • BCDO1_HUMAN antibody
    • BCMO antibody
    • Bcmo1 antibody
    • BCO antibody
    • BCO1 antibody
    • Beta,beta-carotene 15,15'-monooxygenase antibody
    • beta-carotene 15,15'-monooxygenase 1 antibody
    • Beta-carotene dioxygenase 1 antibody
    • FLJ10730 antibody
    see all

Anti-BCMO1 antibody 画像

  • Anti-BCMO1 antibody (ab107418) at 1/100 dilution + WiDr cell line lysates at 35 µg

    Predicted band size : 63 kDa

Anti-BCMO1 antibody (ab107418) 使用論文

ab107418 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab107418.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"