製品の概要

  • 製品名
    Anti-BCMA antibody [MM0108-3D44]
    BCMA 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [MM0108-3D44] to BCMA
  • アプリケーション
    適用あり: WB, Inhibition Assaymore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment (Human) - extracellular domain

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • 精製度
    Protein G purified
  • 特記事項(精製)
    The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and 0.2 µm filtered.
  • ポリ/モノ
    モノクローナル
  • クローン名
    MM0108-3D44
  • アイソタイプ
    IgG2
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab89152 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 20 kDa.
Inhibition Assay Use at an assay dependent dilution.

ターゲット情報

  • 機能
    Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
  • 組織特異性
    Expressed in mature B-cells, but not in T-cells or monocytes.
  • 関連疾患
    Note=A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.
  • 配列類似性
    Contains 1 TNFR-Cys repeat.
  • 細胞内局在
    Cell membrane. Endomembrane system. Perinuclear Golgi-like structures.
  • Information by UniProt
  • 参照データベース
  • 別名
    • B cell maturation antigen antibody
    • B cell maturation factor antibody
    • B cell maturation protein antibody
    • B-cell maturation protein antibody
    • BCM antibody
    • BCMA antibody
    • CD269 antibody
    • CD269 antigen antibody
    • TNFRSF17 antibody
    • TNR17_HUMAN antibody
    • Tumor necrosis factor receptor superfamily member 17 antibody
    see all

プロトコール

参考文献

ab89152 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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