製品の概要

  • 製品名Anti-BCMA antibody
    BCMA 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to BCMA
  • アプリケーション適用あり: ELISA, WBmore details
  • 種交差性

    交差が予測される動物種: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-185 of Human BCMA with tag (AAH58291).

  • ポジティブ・コントロール
    • Recombinant human BCMA.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab54834 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent dilution. Detection limit for recombinant tagged TNFRSF17 is approximately 0.3ng/ml if used as a capture antibody.
WB 1/500 - 1/1000. Detects a band of approximately 46 kDa (predicted molecular weight: 20 kDa). This antibody has only been tested in WB against the recombinant protein used as immunogen. We have no data on the detection of endogenous protein.

ターゲット情報

  • 機能Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
  • 組織特異性Expressed in mature B-cells, but not in T-cells or monocytes.
  • 関連疾患Note=A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.
  • 配列類似性Contains 1 TNFR-Cys repeat.
  • 細胞内局在Cell membrane. Endomembrane system. Perinuclear Golgi-like structures.
  • Information by UniProt
  • 参照データベース
  • 別名
    • B cell maturation antigen antibody
    • B cell maturation factor antibody
    • B cell maturation protein antibody
    • B-cell maturation protein antibody
    • BCM antibody
    • BCMA antibody
    • CD269 antibody
    • CD269 antigen antibody
    • TNFRSF17 antibody
    • TNR17_HUMAN antibody
    • Tumor necrosis factor receptor superfamily member 17 antibody
    see all

Anti-BCMA antibody 画像

  • Anti-BCMA antibody (ab54834) at 1/500 dilution + Recombinant human BCMA at 0.2 µg

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP at 1/5000 dilution

    Predicted band size : 20 kDa
    Observed band size : 46 kDa (why is the actual band size different from the predicted?)

Anti-BCMA antibody (ab54834) 使用論文

ab54834 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"