製品の概要

  • 製品名Anti-Bcl6 antibody, prediluted
    Bcl6 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Bcl6, prediluted
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to internal region of human Bcl6 protein. The amino acid sequence is unavailable.

  • ポジティブ・コントロール
    • Tonsil.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab41846 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報IHC-P: Working dilution: Ready-to-use for 30 min at RT.

    Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Transcriptional repressor which is required for germinal center formation and antibody affinity maturation. Probably plays an important role in lymphomagenesis.
    • 組織特異性Expressed in germinal center T and B cells and in primary immature dendritic cells.
    • 関連疾患Note=Chromosomal aberrations involving BCL6 may be a cause of B-cell non-Hodgkin lymphoma. Translocation t(3;14)(q27;q32); translocation t(3;22)(q27;q11) with immunoglobulin gene regions.
      Note=A chromosomal aberration involving BCL6 may be a cause of a form of B-cell leukemia. Translocation t(3;11)(q27;q23) with POU2AF1/OBF1.
      Note=A chromosomal aberration involving BCL6 may be a cause of lymphoma. Translocation t(3;4)(q27;p11) with ARHH/TTF.
    • 配列類似性Contains 1 BTB (POZ) domain.
      Contains 6 C2H2-type zinc fingers.
    • ドメインThe BTB domain mediates homodimerization. Its dimer interface mediates peptide binding such as to corepressors BCOR and NCOR2.
    • 翻訳後修飾Phosphorylated by MAPK1 in response to antigen receptor activation. Phosphorylation induces its degradation by ubiquitin/proteasome pathway.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • B cell CLL/lymphoma 6 antibody
      • B cell lymphoma 6 protein antibody
      • B-cell lymphoma 5 protein antibody
      • B-cell lymphoma 6 protein antibody
      • BCL 5 antibody
      • Bcl 6 antibody
      • BCL-5 antibody
      • BCL-6 antibody
      • BCL5 antibody
      • BCL6 antibody
      • BCL6_HUMAN antibody
      • BCL6A antibody
      • cys his2 zinc finger transcription factor antibody
      • LAZ 3 antibody
      • LAZ 3 protein antibody
      • LAZ3 antibody
      • Lymphoma associated zinc finger gene on chromosome 3 antibody
      • Protein LAZ-3 antibody
      • ZBTB 27 antibody
      • ZBTB27 antibody
      • Zinc finger and BTB domain containing protein 27 antibody
      • Zinc finger and BTB domain-containing protein 27 antibody
      • Zinc finger protein 51 antibody
      • zinc finger transcription factor BCL6S antibody
      • ZNF 51 antibody
      • ZNF51 antibody
      see all

    Anti-Bcl6 antibody, prediluted 画像

    • Ab41846 staining human Bcl6 in human tonsil by immunohistochemsitry using formalin fixed - paraffin embedded tissue.

    Anti-Bcl6 antibody, prediluted (ab41846) 使用論文

    ab41846 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab41846.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"