製品の概要

  • 製品名Anti-BCCIP antibody
    BCCIP 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to BCCIP
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Lizard, Gorilla
  • 免疫原

    Synthetic peptide corresponding to a region within amino acids 300-350 of Human BCCIP (NP_510868.1).

  • ポジティブ・コントロール
    • Human Breast Carcinoma, Colon Carcinoma, Ovarian Carcinoma and Testicular Seminoma tissues

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab113288 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.

ターゲット情報

  • 機能May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ).
  • 組織特異性Expressed at high levels in testis and skeletal muscle and at lower levels in brain, heart, kidney, liver, lung, ovary, pancreas, placenta, and spleen.
  • 配列類似性Belongs to the BCP1 family.
  • 発生段階Isoform 1 is expressed throughout the cell cycle. Isoform 2 is expressed following mitosis and peaks in the G1/S phase of the cell cycle.
  • 細胞内局在Nucleus. Colocalizes with BRCA2 in discrete nuclear foci.
  • Information by UniProt
  • 参照データベース
  • 別名
    • bccip antibody
    • BCCIP_HUMAN antibody
    • BCCIPalpha antibody
    • BCCIPbeta antibody
    • BRCA2 and CDKN1A interacting protein antibody
    • BRCA2 and CDKN1A-interacting protein antibody
    • BRCA2 and Cip1/p21 interacting protein antibody
    • Cdk inhibitor p21 binding protein antibody
    • P21 and CDK associated protein 1 antibody
    • P21- and CDK-associated protein 1 antibody
    • Protein TOK-1 antibody
    • Protein TOK1 antibody
    • TOK 1 antibody
    • TOK 1alpha antibody
    • TOK 1beta antibody
    • TOK1 antibody
    see all

Anti-BCCIP antibody 画像

  • ab113288, at 1/250 dilution, staining BCCIP in formalin-fixed, paraffin-embedded Human Colon Carcinoma by Immunohistochemistry with DAB staining.
  • ab113288, at 1/250 dilution, staining BCCIP in formalin-fixed, paraffin-embedded Human testicular seminoma by Immunohistochemistry with DAB staining.
  • ab113288, at 1/100 dilution, staining BCCIP in formalin-fixed, paraffin-embedded Human breast carcinoma by Immunohistochemistry. Detection: Red-fluorescent Goat anti-Rabbit IgG-heavy and light chain cross-adsorbed Antibody DyLight® 594 Conjugated used at a dilution of 1/100.

Anti-BCCIP antibody (ab113288) 使用論文

ab113288 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"