The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Predicted molecular weight: 79 kDa.
機能Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation.
関連疾患Bardet-Biedl syndrome 12
配列類似性Belongs to the TCP-1 chaperonin family. BBS12 subfamily.
細胞内局在Cell projection, cilium. Located within the basal body of the primary cilium of differentiating preadipocytes.