Anti-BANP 抗体 (ab72076)
Key features and details
- Rabbit polyclonal to BANP
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG
製品の概要
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製品名
Anti-BANP antibody -
製品の詳細
Rabbit polyclonal to BANP -
由来種
Rabbit -
アプリケーション
適用あり: IHC-P, WBmore details -
種交差性
交差種: Mouse, Human
交差が予測される動物種: Rabbit, Horse, Guinea pig, Cow, Dog, Chimpanzee, Rhesus monkey, Chinese hamster, Orangutan -
免疫原
Synthetic peptide corresponding to a region between residue 425 and the C-terminus (residue 469) of human BANP (TrEMBL entry Q96GJ7)
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7
Preservative: 0.09% Sodium azide
Constituents: 1.815% Tris, 1.764% Sodium citrate, 0.021% PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab72076の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
1/2000 - 1/10000.
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WB |
1/10000 - 1/25000. Predicted molecular weight: 59 kDa.
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特記事項 |
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IHC-P
1/2000 - 1/10000. |
WB
1/10000 - 1/25000. Predicted molecular weight: 59 kDa. |
ターゲット情報
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機能
Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest. -
組織特異性
Down-regulated in breast cancer cell lines. -
配列類似性
Belongs to the BANP/SMAR1 family.
Contains 1 BEN domain. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 54971 Human
- Entrez Gene: 53325 Mouse
- Omim: 611564 Human
- SwissProt: Q8N9N5 Human
- SwissProt: Q8VBU8 Mouse
- Unigene: 461705 Human
- Unigene: 287163 Mouse
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別名
- AAH09424 antibody
- Banp antibody
- BANP_HUMAN antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of mouse renal cell tissue labelling BANP with ab72076 at 1/5000 (0.2µg/ml). Setection: DAB.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human lung carcinoma tissue labelling BANP with ab72076 at 1/5000 (0.2µg/ml). Setection: DAB.
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All lanes : Anti-BANP antibody (ab72076) at 0.1 µg/ml
Lane 1 : HeLa whole cell lysate
Lane 2 : HEK293T whole cell lysate
Lane 3 : NIH 3T3 whole cell lysate
Lysates/proteins at 50 µg per lane.
Predicted band size: 59 kDa
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab72076 は論文での使用が確認できていません。