Anti-Band 3 抗体 - Aminoterminal end (ab55830)

製品の概要

  • 製品名Anti-Band 3 antibody - Aminoterminal end
    Band 3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Band 3 - Aminoterminal end
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Recombinant Fragment
    交差が予測される動物種: Human
  • 免疫原

    A synthetic peptide corresponding to N-terminal residues of human Band 3

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.01% Sodium Azide
    Constituents: 50% Glycerol, PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab55830 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 102 kDa. for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA Use at an assay dependent dilution.

ターゲット情報

  • 機能Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Major integral membrane glycoprotein of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride-bicarbonate exchange in the kidney, and is required for normal acidification of the urine.
  • 組織特異性Detected in erythrocytes (at protein level) (PubMed:7506871, PubMed:26542571). Isoform 2 is expressed in kidney (at protein level) (PubMed:7506871).
  • 関連疾患Ovalocytosis, Southeast Asian
    Spherocytosis 4
    Renal tubular acidosis, distal, autosomal dominant
    Renal tubular acidosis, distal, with hemolytic anemia
    Renal tubular acidosis, distal, with normal red cell morphology
    Cryohydrocytosis
  • 配列類似性Belongs to the anion exchanger (TC 2.A.31) family.
  • 翻訳後修飾Phosphorylated on Tyr-8 and Tyr-21 most likely by SYK. PP1-resistant phosphorylation that precedes Tyr-359 and Tyr-904 phosphorylation.
    Phosphorylated on Tyr-359 and Tyr-904 most likely by LYN. PP1-inhibited phosphorylation that follows Tyr-8 and Tyr-21 phosphorylation.
    N-glycosylated.
  • 細胞内局在Cell membrane. Basolateral cell membrane. Detected in the erythrocyte cell membrane and on the basolateral membrane of alpha-intercalated cells in the collecting duct in the kidney.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AE 1 antibody
    • AE1 antibody
    • Anion exchange protein 1 antibody
    • Anion exchanger 1 antibody
    • B3AT_HUMAN antibody
    • Band 3 anion transport protein antibody
    • BND3 antibody
    • CD233 antibody
    • DI antibody
    • Diego blood group antibody
    • EMPB3 antibody
    • EPB3 antibody
    • Erythrocyte membrane protein band 3 antibody
    • Erythroid anion exchange protein antibody
    • FR antibody
    • Froese blood group antibody
    • RTA1A antibody
    • SLC4A1 antibody
    • Solute carrier family 4 anion exchanger member 1 antibody
    • Solute carrier family 4 member 1 antibody
    • SW antibody
    • Swann blood group antibody
    • Waldner blood group antibody
    • WD antibody
    • WD1 antibody
    • WR antibody
    • Wright blood group antibody
    see all

Anti-Band 3 antibody - Aminoterminal end (ab55830) 使用論文

ab55830 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab55830.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"