Anti-Bak 抗体 - Aminoterminal end (ab62486)

製品の概要

  • 製品名Anti-Bak antibody - Aminoterminal end
    Bak 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Bak - Aminoterminal end
  • 特異性This antibody reacts with Bak
  • アプリケーション適用あり: WB, ICCmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    A 13 amino acid synthetic peptide from near the amino terminus of human Bak

  • ポジティブ・コントロール
    • L1210 cell lysates and L1210 cells

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度Ion Exchange Chromatography
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab62486 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 23 kDa).
ICC Use a concentration of 2 µg/ml.

ターゲット情報

  • 機能In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.
  • 組織特異性Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle.
  • 配列類似性Belongs to the Bcl-2 family.
  • ドメインIntact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
  • 細胞内局在Mitochondrion membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Apoptosis regulator BAK antibody
    • BAK antibody
    • BAK like antibody
    • Bak NT antibody
    • BAK_HUMAN antibody
    • Bak1 antibody
    • Bcl 2 homologous antagonist/killer antibody
    • Bcl 2 like 7 protein antibody
    • Bcl-2 homologous antagonist/killer antibody
    • Bcl-2-like protein 7 antibody
    • BCL2 antagonist/killer 1 antibody
    • Bcl2 like 7 Protein antibody
    • Bcl2-L-7 antibody
    • BCL2L7 antibody
    • CDN1 antibody
    • Cell death inhibitor 1 antibody
    • MGC117255 antibody
    • MGC3887 antibody
    • NBak antibody
    • Pro apoptotic protein BAK antibody
    see all

Anti-Bak antibody - Aminoterminal end 画像

  • Lane 1 : Anti-Bak antibody - Aminoterminal end (ab62486) at 1 µg/ml
    Lane 2 : Anti-Bak antibody - Aminoterminal end (ab62486) at 2 µg/ml

    Lane 1 : L1210 cell lysates
    Lane 2 : L1210 cell lysates

    Lysates/proteins at 15 µg per lane.

    Secondary
    Anti rabbit IgG secondary antibody

    Predicted band size : 23 kDa
    Observed band size : 28 kDa (why is the actual band size different from the predicted?)
  • Immunocytochemistry of Bak in L1210 cells with ab62486 antibody at 2 µg/ml.

Anti-Bak antibody - Aminoterminal end (ab62486) 使用論文

ab62486 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab62486.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"