製品の概要

  • 製品名Anti-Bak antibody
    Bak 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Bak
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide, corresponding to amino acids 23-38 (with C-terminal Lysine added) of Human Bak.

  • ポジティブ・コントロール
    • A431 whole cell lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 15mM Sodium Azide
    Constituents: 0.01M PBS, pH 7.4
  • Concentration information loading...
  • 精製度IgG fraction
  • 特記事項(精製)Whole antiserum is fractionated and then further purified by ion-exchange chromatography to provide the IgG fraction of antiserum that is essentially free of other rabbit serum proteins.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab10430 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
IHC-P
  • 追加情報IHC-P: 1/100 (human colon adenocarcinoma).
    WB: 1/2000. Detects a band of approximately 28 kDa.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.
    • 組織特異性Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle.
    • 配列類似性Belongs to the Bcl-2 family.
    • ドメインIntact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
    • 細胞内局在Mitochondrion membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Apoptosis regulator BAK antibody
      • BAK antibody
      • BAK like antibody
      • Bak NT antibody
      • BAK_HUMAN antibody
      • Bak1 antibody
      • Bcl 2 homologous antagonist/killer antibody
      • Bcl 2 like 7 protein antibody
      • Bcl-2 homologous antagonist/killer antibody
      • Bcl-2-like protein 7 antibody
      • BCL2 antagonist/killer 1 antibody
      • Bcl2 like 7 Protein antibody
      • Bcl2-L-7 antibody
      • BCL2L7 antibody
      • CDN1 antibody
      • Cell death inhibitor 1 antibody
      • MGC117255 antibody
      • MGC3887 antibody
      • NBak antibody
      • Pro apoptotic protein BAK antibody
      see all

    Anti-Bak antibody (ab10430) 使用論文

    ab10430 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab10430.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"