製品の概要

  • 製品名
  • 製品の詳細
    Mouse monoclonal to Bag5
  • アプリケーション
    適用あり: WB, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-448 of Human Bag5

  • 特記事項

    Abcam is committed to meeting high standards of ethical manufacturing and has decided to discontinue this product by June 2019 as it has been generated by the ascites method. We are sorry for any inconvenience this may cause.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab56738 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 51 kDa.
ICC/IF Use at an assay dependent concentration. PubMed: 24475098

ターゲット情報

  • 機能
    Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2 (By similarity). May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding.
  • 配列類似性
    Contains 5 BAG domains.
  • ドメイン
    The fifth BAG domain is responsible for the interaction with HSP70 nucleotide-binding domain.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BAG family molecular chaperone regulator 5 antibody
    • BAG-5 antibody
    • BAG5 antibody
    • BAG5_HUMAN antibody
    • Bcl 2 associated athanogene 5 antibody
    • Bcl-2-associated athanogene 5 antibody
    • BCL2 associated athanogene 5 antibody
    • KIAA0873 antibody
    see all

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  • Predicted band size : 51 kDa
    Bag5 antibody (ab56738) at 1ug/lane + Jurkat cell lysate at 25ug/lane.

参考文献

This product has been referenced in:
  • Qin LX  et al. BAG5 Interacts with DJ-1 and Inhibits the Neuroprotective Effects of DJ-1 to Combat Mitochondrial Oxidative Damage. Oxid Med Cell Longev 2017:5094934 (2017). Read more (PubMed: 28348719) »
  • Wang X  et al. BAG5 protects against mitochondrial oxidative damage through regulating PINK1 degradation. PLoS One 9:e86276 (2014). ICC/IF ; Human . Read more (PubMed: 24475098) »

See all 4 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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