製品の概要

  • 製品名Anti-Bag3 antibody
    Bag3 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Bag3
  • アプリケーション適用あり: WB, IHC-P, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide:

    C-SSMTDTPGNPAAP

    , corresponding to C terminal amino acids 563-575 of Human Bag3.

  • ポジティブ・コントロール
    • Human Heart, Human Skeletal Muscle and Human Placenta tissue

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab112016 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.1 - 0.3 mg/ml. Predicted molecular weight: 62 kDa.
IHC-P Use a concentration of 3.75 µg/ml.
ELISA 1/8000.

ターゲット情報

  • 機能Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Has anti-apoptotic activity.
  • 関連疾患Defects in BAG3 are the cause of myopathy myofibrillar BAG3-related (MFM-BAG3) [MIM:612954]. A neuromuscular disorder that results in early-onset, severe, progressive, diffuse muscle weakness associated with cardiomyopathy, severe respiratory insufficiency during adolescence, and a rigid spine in some patients. At ultrastructural level, muscle fibers display structural alterations consisting of replacement of the normal myofibrillar markings by small, dense granules, or larger hyaline masses, or amorphous material.
  • 配列類似性Contains 1 BAG domain.
    Contains 2 WW domains.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BAG 3 antibody
    • BAG family molecular chaperone regulator 3 antibody
    • BAG-3 antibody
    • Bag3 antibody
    • BAG3_HUMAN antibody
    • Bcl 2 binding protein antibody
    • Bcl-2-associated athanogene 3 antibody
    • Bcl-2-binding protein Bis antibody
    • BCL2 associated athanogene 3 antibody
    • BCL2 binding athanogene 3 antibody
    • BIS antibody
    • CAIR 1 antibody
    • Docking protein CAIR 1 antibody
    • Docking protein CAIR-1 antibody
    • MFM6 antibody
    see all

Anti-Bag3 antibody 画像

  • Immunohistochemical analysis of Bag3 expression in formalin-fixed, paraffin-embedded Human heart tissue using ab112016 at 3.75 µg/ml.
  • Immunohistochemical analysis of Bag3 expression in formalin-fixed, paraffin-embedded Human skeletal muscle tissue using ab112016 at 3.75 µg/ml.
  • Immunohistochemical analysis of Bag3 expression in formalin-fixed, paraffin-embedded Human placenta tissue using ab112016 at 3.75 µg/ml.

Anti-Bag3 antibody (ab112016) 使用論文

ab112016 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"