製品の概要

  • 製品名Anti-B7H4 antibody
    B7H4 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to B7H4
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Horse, Cow, Dog, Pig, Chimpanzee, Macaque Monkey
  • 免疫原

    Synthetic peptide: C-

    SKGKGNANLEYK

    , corresponding to amino acids 135-146 of Human B7H4 (NP_078902.2)

  • ポジティブ・コントロール
    • Human Lung, Spleen and Thymus lysates

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab77281 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.5 - 1.5 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 31 kDa).
ELISA Use at an assay dependent dilution. Peptide ELISA: antibody detection limit dilution 1:64000.

ターゲット情報

  • 機能Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.
  • 組織特異性Overexpressed in breast, ovarian, endometrial, renal cell (RCC) and non-small-cell lung cancers (NSCLC). Expressed on activated T- and B-cells, monocytes and dendritic cells, but not expressed in most normal tissues (at protein level). Widely expressed, including in kidney, liver, lung, ovary, placenta, spleen and testis.
  • 配列類似性Belongs to the immunoglobulin superfamily. BTN/MOG family.
    Contains 2 Ig-like V-type (immunoglobulin-like) domains.
  • 翻訳後修飾N-glycosylated.
  • 細胞内局在Cell membrane. Expressed at the cell surface. A soluble form has also been detected.
  • Information by UniProt
  • 参照データベース
  • 別名
    • B7 family member, H4 antibody
    • B7 H4 antibody
    • B7 homolog 4 antibody
    • B7 superfamily member 1 antibody
    • B7 superfamily, member 1 antibody
    • B7-H4 antibody
    • B7h.5 antibody
    • B7h4 antibody
    • B7S1 antibody
    • B7x antibody
    • BC032925 antibody
    • Immune costimulatory protein B7-H4 antibody
    • Immune costimulatory protein B7H4 antibody
    • MGC41287 antibody
    • PRO1291 antibody
    • Protein B7S1 antibody
    • RP11 229A19.4 antibody
    • T cell costimulatory molecule B7x antibody
    • T-cell costimulatory molecule B7x antibody
    • V set domain-containing T cell activation inhibitor 1 antibody
    • V-set domain-containing T-cell activation inhibitor 1 antibody
    • VCTN1 antibody
    • Vtcn1 antibody
    • VTCN1_HUMAN antibody
    see all

Anti-B7H4 antibody 画像

  • Anti-B7H4 antibody (ab77281) at 0.5 µg/ml + Human Pancrease lysate in RIPA Buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 31 kDa
    Observed band size : 28 kDa (why is the actual band size different from the predicted?)

Anti-B7H4 antibody (ab77281) 使用論文

ab77281 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us. I have inquired withthe lab about several antibodies regarding their immunogen sequence. For the following 3 antibodies I already have results: ab56807: homology = 98% thus is likely to crossreact ab77281: hom...

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