製品の概要

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab53511 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 100 kDa (predicted molecular weight: 79 kDa).
IHC-Fr 1/300. PubMed: 24886974
ELISA Use at an assay dependent concentration.

Peptide ELISA: antibody detection limit dilution 1:32,000.

ターゲット情報

  • 機能
    Transcription factor involved in the regulation of cell survival, proliferation, and differentiation. Transactivates the expression of the CLU gene.
  • 配列類似性
    Contains 3 HTH myb-type DNA-binding domains.
  • 翻訳後修飾
    Phosphorylated by cyclin A/CDK2 during S-phase. Phosphorylation at Thr-520 is probably involved in transcriptional activity.
  • 細胞内局在
    Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • B-Myb antibody
    • BMyB antibody
    • MGC15600 antibody
    • MYB L2 antibody
    • Myb related protein B antibody
    • Myb-like protein 2 antibody
    • Myb-related protein B antibody
    • MybB antibody
    • MYBB_HUMAN antibody
    • MYBL 2 antibody
    • Mybl2 antibody
    • v myb avian myeloblastosis viral oncogene homolog like 2 antibody
    • v myb myeloblastosis viral oncogene homolog (avian) like 2 antibody
    • v myb myeloblastosis viral oncogene homolog like 2 antibody
    see all

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参考文献

This product has been referenced in:
  • Rosa-Ribeiro R  et al. Transcription factors involved in prostate gland adaptation to androgen deprivation. PLoS One 9:e97080 (2014). IHC-Fr ; Rat . Read more (PubMed: 24886974) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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