製品の概要

  • 製品名Anti-ATXN10 antibody
    ATXN10 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ATXN10
  • アプリケーション適用あり: IPmore details
    適用なし: WB
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Guinea pig, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region between residues 1 and 50 of human ATXN10 (NP_037368.1)

  • ポジティブ・コントロール
    • HeLa whole cell lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: 8mM PBS, 60mM Citrate, 150mM Tris, pH 7-8
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab72101 was affinity purified using an epitope specific to ATXN10 immobilized on solid support.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab72101 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP Use at 2-5 µg/mg of lysate.
  • 追加情報Is unsuitable for WB.
  • ターゲット情報

    • 機能Necessary for the survival of cerebellar neurons (By similarity). Induces neuritogenesis by activating the Ras-MAP kinase pathway (By similarity). May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.
    • 組織特異性Expressed in the central nervous system.
    • 関連疾患Defects in ATXN10 are the cause of spinocerebellar ataxia type 10 (SCA10) [MIM:603516]. Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCA10 is an autosomal dominant cerebellar ataxia (ADCA).
    • 配列類似性Belongs to the ataxin-10 family.
    • 細胞内局在Cytoplasm > perinuclear region.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Ataxin 10 antibody
      • Ataxin-10 antibody
      • ATX10_HUMAN antibody
      • Atxn10 antibody
      • Brain protein E46 homolog antibody
      • E46L antibody
      • FLJ37990 antibody
      • HUMEEP antibody
      • Like mouse brain protein E46 antibody
      • OTTHUMP00000197383 antibody
      • SCA10 antibody
      • Spinocerebellar ataxia 10 antibody
      • Spinocerebellar ataxia type 10 protein antibody
      see all

    Anti-ATXN10 antibody 画像

    • Detection of ATXN10 by Western Blot of Immunprecipitate.
      anti-ATXN10 at 1µg/ml staining ATXN10 in HeLa whole cell lysate immunoprecipitated using ab72101 at 3µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
      Detection: Chemiluminescence with exposure time of 10 seconds.

    Anti-ATXN10 antibody (ab72101) 使用論文

    ab72101 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab72101.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"