製品の概要

  • 製品名Anti-ATXN10 antibody
    ATXN10 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ATXN10
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Guinea pig, Cow, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 8-57 (PARLSGVMVP APIQDLEALR ALTALFKEQR NRETAPRTIF QRVLDILKKS) of Human ATXN10 (NM_013236).

  • ポジティブ・コントロール
    • 293T cell lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーConstituents: 97% PBS, 2% Sucrose
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab116528 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 53 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Necessary for the survival of cerebellar neurons (By similarity). Induces neuritogenesis by activating the Ras-MAP kinase pathway (By similarity). May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.
  • 組織特異性Expressed in the central nervous system.
  • 関連疾患Defects in ATXN10 are the cause of spinocerebellar ataxia type 10 (SCA10) [MIM:603516]. Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCA10 is an autosomal dominant cerebellar ataxia (ADCA).
  • 配列類似性Belongs to the ataxin-10 family.
  • 細胞内局在Cytoplasm > perinuclear region.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Ataxin 10 antibody
    • Ataxin-10 antibody
    • ATX10_HUMAN antibody
    • Atxn10 antibody
    • Brain protein E46 homolog antibody
    • E46L antibody
    • FLJ37990 antibody
    • HUMEEP antibody
    • Like mouse brain protein E46 antibody
    • OTTHUMP00000197383 antibody
    • SCA10 antibody
    • Spinocerebellar ataxia 10 antibody
    • Spinocerebellar ataxia type 10 protein antibody
    see all

Anti-ATXN10 antibody 画像

  • Anti-ATXN10 antibody (ab116528) at 1 µg/ml + 293T cell lysate at 10 µg

    Predicted band size : 53 kDa

Anti-ATXN10 antibody (ab116528) 使用論文

ab116528 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"