製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to ATTY
  • アプリケーション
    適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 285-315 of Human ATTY (NP_000344).

  • ポジティブ・コントロール
    • K562 cell line lysates. Human hepatocarcinoma tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab103992 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 50 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能
    Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. Can catalyze the reverse reaction, using glutamic acid, with 2-oxoglutarate as cosubstrate (in vitro). Has no transaminase activity towards phenylalanine.
  • パスウェイ
    Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 2/6.
  • 関連疾患
    Defects in TAT are the cause of tyrosinemia type 2 (TYRO2) [MIM:276600]; also known as Richner-Hanhart syndrome. TYRO2 is an inborn error of metabolism characterized by elevations of tyrosine in the blood and urine, and oculocutaneous manifestations. Typical features include palmoplantar keratosis, painful corneal ulcers, and mental retardation.
  • 配列類似性
    Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ATTY_HUMAN antibody
    • L-tyrosine:2-oxoglutarate aminotransferase antibody
    • TAT antibody
    • Tyrosine aminotransferase antibody
    • Tyrosine aminotransferase, cytosolic antibody
    see all

画像

  • Anti-ATTY antibody (ab103992) at 1/100 dilution + K562 cell line lysates at 35 µg

    Predicted band size : 50 kDa
  • ab103992 at 1/50 dilution staining ATTY by immunohistochemistry in formalin fixed and paraffin embedded Human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining

参考文献

ab103992 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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