製品の概要

  • 製品名Anti-ATP5A antibody
    ATP5A 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ATP5A
  • アプリケーション適用あり: WB, IHC-P, ELISAmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat
  • 免疫原

    Synthetic peptide, conjugated to KLH, from internal sequence amino acids of Human ATP5A (NP_004037.1).

  • ポジティブ・コントロール
    • Human breast and heart tissues; 293 and RAW264.7 cell extracts.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab118482 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 60 kDa.
IHC-P Use a concentration of 5 µg/ml.
ELISA 1/40000.

ターゲット情報

  • 機能Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. Subunit alpha does not bear the catalytic high-affinity ATP-binding sites.
  • 組織特異性Fetal lung, heart, liver, gut and kidney. Expressed at higher levels in the fetal brain, retina and spinal cord.
  • 配列類似性Belongs to the ATPase alpha/beta chains family.
  • 翻訳後修飾The N-terminus is blocked.
  • 細胞内局在Mitochondrion inner membrane. Peripheral membrane protein.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ATP synthase alpha chain, mitochondrial antibody
    • ATP synthase subunit alpha antibody
    • ATP synthase subunit alpha mitochondrial antibody
    • ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle antibody
    • ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, 1 antibody
    • ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 1, cardiac muscle antibody
    • ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 2, non-cardiac muscle-like 2 antibody
    • ATP sythase (F1 ATPase) alpha subunit antibody
    • ATP5A antibody
    • Atp5a1 antibody
    • ATP5AL2 antibody
    • ATPA_HUMAN antibody
    • ATPM antibody
    • Epididymis secretory sperm binding protein Li 123m antibody
    • hATP1 antibody
    • HEL-S-123m antibody
    • MC5DN4 antibody
    • mitochondrial antibody
    • Mitochondrial ATP synthetase antibody
    • Mitochondrial ATP synthetase oligomycin resistant antibody
    • Modifier of Min 2 mouse homolog antibody
    • Modifier of Min 2, mouse, homolog of antibody
    • MOM2 antibody
    • OMR antibody
    • ORM antibody
    • OTTHUMP00000163475 antibody
    see all

Anti-ATP5A antibody 画像

  • ab118482 at 5µg/ml staining ATP5A in Formalin-fixed, Paraffin-embedded Human breast tissue by immunohistochemistry.
  • ab118482 at 5µg/ml staining ATP5A in Formalin-fixed, Paraffin-embedded Human heart tissue by immunohistochemistry.
  • All lanes : Anti-ATP5A antibody (ab118482) at 1/500 dilution

    Lane 1 : RAW264.7 cell extract
    Lane 2 : 293 cell extract
    Lane 3 : RAW264.7 cell extract with sythesized immunizing peptide


    Predicted band size : 60 kDa

Anti-ATP5A antibody (ab118482) 使用論文

ab118482 has not yet been referenced specifically in any publications.

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I have been in touch with the lab regarding the sequence homology of the immunogens for the anti-ATP5A products and E.coli.

ab136082: The immunogen is aa200-250 of human ATP synthase subunit alpha with a...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"