製品の概要
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製品名Anti-ATG9B antibody
ATG9B 一次抗体 製品一覧 -
製品の詳細Rabbit polyclonal to ATG9B
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由来種Rabbit
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アプリケーション適用あり: WB, IHC-P, ICC, ELISAmore details
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種交差性交差種: Human
交差が予測される動物種: Mouse, Rat
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免疫原
Synthetic peptide conjugated to KLH from the C-terminus of Human ATG9B
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ポジティブ･コントロール
- Human placenta tissue, Human spleen tissue
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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バッファーPreservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
精製度Immunogen affinity purified
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab117591 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 101 kDa. | |
| IHC-P | Use a concentration of 5 µg/ml. | |
| ICC | Use a concentration of 5 - 10 µg/ml. | |
| ELISA | Use at an assay dependent concentration. |
ターゲット情報
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機能Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle.
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組織特異性Highly expressed in placenta (trophoblast cells) and pituitary gland. Not expressed in vascular endothelial.
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配列類似性Belongs to the ATG9 family.
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細胞内局在Cytoplasmic vesicle, autophagosome membrane. Under amino acid starvation or rapamycin treatment, redistributes from a juxtanuclear clustered pool to a dispersed peripheral cytosolic pool. The starvation-induced redistribution depends on ULK1 and ATG13.
- Information by UniProt
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参照データベース
- Entrez Gene: 285973 Human
- Entrez Gene: 213948 Mouse
- Entrez Gene: 499973 Rat
- Omim: 612205 Human
- SwissProt: Q674R7 Human
- SwissProt: Q6EBV9 Mouse
- Unigene: 707300 Human
- Unigene: 716846 Human
see all -
別名
- APG9 like 2 antibody
- APG9-like 2 antibody
- Apg912 antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ATG9B antibody (ab117591)Formalin fixed, paraffin embedded Human placenta tissue labelled with ab117591 at 5 µg/ml -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ATG9B antibody (ab117591)Formalin fixed, paraffin embedded Human spleen tissue labelled with ab117591 at 5 µg/ml
プロトコール
参考文献
This product has been referenced in:
- Ma Z et al. The role ofCRPandATG9Bexpression in clear cell renal cell carcinoma. Biosci Rep 37:N/A (2017). Read more (PubMed: 28923830) »
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"