Anti-ATG9B 抗体 (ab117591)
Key features and details
- Rabbit polyclonal to ATG9B
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-ATG9B antibody
ATG9B 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to ATG9B -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat -
免疫原
Synthetic peptide conjugated to KLH from the C-terminus of Human ATG9B
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ポジティブ・コントロール
- Human placenta tissue, Human spleen tissue
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.4
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab117591の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
Use a concentration of 5 µg/ml.
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特記事項 |
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IHC-P
Use a concentration of 5 µg/ml. |
ターゲット情報
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機能
Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. -
組織特異性
Highly expressed in placenta (trophoblast cells) and pituitary gland. Not expressed in vascular endothelial. -
配列類似性
Belongs to the ATG9 family. -
細胞内局在
Cytoplasmic vesicle, autophagosome membrane. Under amino acid starvation or rapamycin treatment, redistributes from a juxtanuclear clustered pool to a dispersed peripheral cytosolic pool. The starvation-induced redistribution depends on ULK1 and ATG13. - Information by UniProt
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参照データベース
- Entrez Gene: 285973 Human
- Entrez Gene: 213948 Mouse
- Entrez Gene: 499973 Rat
- Omim: 612205 Human
- SwissProt: Q674R7 Human
- SwissProt: Q6EBV9 Mouse
- Unigene: 707300 Human
- Unigene: 716846 Human
see all -
別名
- APG9 like 2 antibody
- APG9-like 2 antibody
- Apg912 antibody
see all
画像
データシートおよび資料
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Datasheet download
参考文献 (4)
ab117591 は 4 報の論文で使用されています。
- Liang W et al. Aging is associated with a decline in Atg9b-mediated autophagosome formation and appearance of enlarged mitochondria in the heart. Aging Cell 19:e13187 (2020). PubMed: 32627317
- Liao Y et al. Excessive ER-phagy mediated by the autophagy receptor FAM134B results in ER stress, the unfolded protein response, and cell death in HeLa cells. J Biol Chem 294:20009-20023 (2019). PubMed: 31748416
- Zhao R et al. Alliin alleviates myocardial ischemia-reperfusion injury by promoting autophagy. Biochem Biophys Res Commun 512:236-243 (2019). PubMed: 30885435
- Ma Z et al. The role ofCRPandATG9Bexpression in clear cell renal cell carcinoma. Biosci Rep 37:N/A (2017). PubMed: 28923830