製品の概要

  • 製品名Anti-ATG16L1 antibody
    ATG16L1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ATG16L1
  • アプリケーション適用あり: ICC/IF, WB, ICCmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to 18 amino acids from near the center of human ATG16L1 (NP_110430).

  • ポジティブ・コントロール
    • HeLa cells

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab106354 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 0.25 - 0.5 µg/ml. Predicted molecular weight: 68 kDa.
ICC Use a concentration of 2 µg/ml.

ターゲット情報

  • 機能Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.
  • 関連疾患Inflammatory bowel disease 10
  • 配列類似性Belongs to the WD repeat ATG16 family.
    Contains 7 WD repeats.
  • 翻訳後修飾Proteolytic cleavage by activated CASP3 leads to degradation and may regulate autophagy upon cellular stress and apoptotic stimuli.
  • 細胞内局在Cytoplasm. Preautophagosomal structure membrane. Recruited to omegasomes membranes by WIPI2. Omegasomes are endoplasmic reticulum connected strutures at the origin of preautophagosomal structures. Localized to preautophagosomal structure (PAS) where it is involved in the membrane targeting of ATG5. Localizes also to discrete punctae along the ciliary axoneme.
  • Information by UniProt
  • 参照データベース
  • 製品の状態There are 4 isoforms produced by alternative splicing.
  • 別名
    • A16L1_HUMAN antibody
    • APG16 like 1 antibody
    • APG16-like 1 antibody
    • APG16L antibody
    • APG16L beta antibody
    • ATG16 autophagy related 16 like 1 antibody
    • ATG16 autophagy related 16-like 1 (S. cerevisiae) antibody
    • ATG16A antibody
    • ATG16L antibody
    • Atg16l1 antibody
    • Autophagy related protein 16 1 antibody
    • Autophagy-related protein 16-1 antibody
    • FLJ00045 antibody
    • FLJ10035 antibody
    • FLJ10828 antibody
    • FLJ22677 antibody
    • IBD10 antibody
    • OTTHUMP00000164391 antibody
    • OTTHUMP00000164393 antibody
    • OTTHUMP00000165876 antibody
    • OTTHUMP00000165877 antibody
    • WD repeat domain 30 antibody
    • WDR30 antibody
    see all

Anti-ATG16L1 antibody 画像

  • Lane 1 : Anti-ATG16L1 antibody (ab106354) at 0.25 µg/ml
    Lane 2 : Anti-ATG16L1 antibody (ab106354) at 0.5 µg/ml

    Lane 1 : HeLa Cell lysate
    Lane 2 : HeLa Cell lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 68 kDa
  • Immunocytochemistry of ATG16 in HeLa cells with ATG16 antibody (ab106354) at 2 µg/ml.
  • Immunofluorescence of ATG16 in Hela cells using ab106354 at 4 ug/ml.

Anti-ATG16L1 antibody (ab106354) 使用論文

ab106354 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"