製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to AT11A
  • アプリケーション
    適用あり: ELISA, ICC, WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal of Human AT11A.

  • ポジティブ・コントロール
    • Human testis tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab117577 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent concentration.
ICC Use at an assay dependent concentration.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 129 kDa.
IHC-P Use a concentration of 5 µg/ml.

ターゲット情報

  • 機能
    Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable). May be involved in the uptake of farnesyltransferase inhibitor drugs, such as lonafarnib.
  • 配列類似性
    Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
  • 細胞内局在
    Cell membrane. Early endosome. Recycling endosome. Endoplasmic reticulum. Exit from the endoplasmic reticulum requires the presence of TMEM30A, but not TMEM30B. In the presence of TMEM30A, predominantly located in the plasma membrane.
  • Information by UniProt
  • 参照データベース
  • 製品の状態
    P-type ATPases, such as ATP11A, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes.
  • 別名
    • AT11A_HUMAN antibody
    • Atp11a antibody
    • ATPase class VI type 11A antibody
    • ATPase IS antibody
    • ATPIH antibody
    • ATPIS antibody
    • P4-ATPase flippase complex alpha subunit ATP11A antibody
    • Probable phospholipid-transporting ATPase IH antibody
    see all

Anti-AT11A antibody 画像

  • Immunohistochemical analysis of AT11A expression in Formalin-Fixed, Paraffin-Embedded Human Testis using 5 µg/ml ab117577.

Anti-AT11A antibody (ab117577) 使用論文

ab117577 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab117577.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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