製品の概要

  • 製品名Anti-AT11A antibody
    AT11A 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to AT11A
  • 特異性ab105351 is predicted to not cross react with AT11B. At least two isoforms of AT11A are known to exist; this antibody will recognize both.
  • アプリケーション適用あり: ICC/IF, WB, ICCmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    A 19 amino acid peptide from a region within the N terminus of Human AT11A (NP_115565).

  • ポジティブ・コントロール
    • WB: K562 cell lysate ICC: K562 cells

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab105351 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 130 kDa.
ICC Use a concentration of 10 µg/ml.

ターゲット情報

  • 機能Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable). May be involved in the uptake of farnesyltransferase inhibitor drugs, such as lonafarnib.
  • 配列類似性Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
  • 細胞内局在Cell membrane. Early endosome. Recycling endosome. Endoplasmic reticulum. Exit from the endoplasmic reticulum requires the presence of TMEM30A, but not TMEM30B. In the presence of TMEM30A, predominantly located in the plasma membrane.
  • Information by UniProt
  • 参照データベース
  • 製品の状態P-type ATPases, such as ATP11A, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes.
  • 別名
    • AT11A_HUMAN antibody
    • Atp11a antibody
    • ATPase class VI type 11A antibody
    • ATPase IS antibody
    • ATPIH antibody
    • ATPIS antibody
    • P4-ATPase flippase complex alpha subunit ATP11A antibody
    • Probable phospholipid-transporting ATPase IH antibody
    see all

Anti-AT11A antibody 画像

  • Immunofluorescence of ATP11A in K562 cells with ab105351 at 20 ug/mL.

  • All lanes : Anti-AT11A antibody (ab105351) at 1 µg/ml

    Lane 1 : K562 cell lysate
    Lane 2 : K562 cell lysate with blocking peptide

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 130 kDa
  • ab105351, at 10 µg/ml, staining AT11A in K562 cells by Immunocytochemistry.

Anti-AT11A antibody (ab105351) 使用論文

ab105351 has not yet been referenced specifically in any publications.

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Thank you for your reply and thank you for trying the mouse samples as well! I am very sorry that these3 antibodies did not perform as expected. I would be happy to offer you either a free of charge replacement for each antibody, or a credit or r...

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Thank you for your phone call. I am sorry to hear that these antibodies are not providing satisfactory results so far. The details provided will enable us to investigate this case and will provide us with vital information for monitoring product qual...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"