製品の概要

  • 製品名Anti-ASXL2 antibody
    ASXL2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ASXL2
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 575-624 (EEAPVSWEKR PRVTENRQHQ QPFQVSPQPF LNRGDRIQVR KVPPLKIPVS) of Human ASXL2 (NP_060733)

  • ポジティブ・コントロール
    • NCI-H226 Cell Lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab106540 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 154 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility.
  • 関連疾患Note=A chromosomal aberration involving ASXL2 is a cause of therapy-related myelodysplastic syndrome. Translocation t(2;8)(p23;p11.2) with MYST3 generates a MYST3-ASXL2 fusion protein.
  • 配列類似性Belongs to the Asx family.
    Contains 1 PHD-type zinc finger.
  • ドメインContains two Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs, which may be required for an association with nuclear receptors.
  • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 製品の状態There are 2 isoforms produced by alternative splicing.
  • 別名
    • additional sex combs like 2 (Drosophila) antibody
    • Additional sex combs like 2 antibody
    • Additional sex combs like protein 2 antibody
    • Additional sex combs-like protein 2 antibody
    • ASXH2 antibody
    • ASXL 2 antibody
    • ASXL2 antibody
    • ASXL2_HUMAN antibody
    • DKFZp686C1968 antibody
    • FLJ10898 antibody
    • KIAA1685 antibody
    • Polycomb group protein ASXH2 antibody
    • Putative Polycomb group protein ASXL2 antibody
    see all

Anti-ASXL2 antibody 画像

  • Anti-ASXL2 antibody (ab106540) at 1 µg/ml + 10 µg NCI-H226 Cell Lysate

    Predicted band size : 154 kDa

Anti-ASXL2 antibody (ab106540) 使用論文

ab106540 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"