製品の概要

  • 製品名
    Anti-ASXL1 antibody [2049C2a]
    ASXL1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [2049C2a] to ASXL1
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment of ASXL1 (Human)

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab50817 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent dilution. Predicted molecular weight: 165 kDa.

ターゲット情報

  • 機能
    Probable Polycomb group (PcG) protein. Non-catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1).
  • 組織特異性
    Widely expressed at low level. Expressed in heart, brain, skeletal muscle, placenta, pancreas, spleen, prostate, small intestine, colon, peripheral blood, leukocytes, bone marrow and fetal liver. Highly expressed in testes.
  • 配列類似性
    Belongs to the Asx family.
    Contains 1 PHD-type zinc finger.
  • ドメイン
    Contains one Leu-Xaa-Xaa-Leu-Leu (LXXLL) motif, which may be required for an association with nuclear receptors.
  • 細胞内局在
    Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Additional sex combs like 1 (Drosophila) antibody
    • Additional sex combs like protein 1 antibody
    • Additional sex combs-like protein 1 antibody
    • ASXL1 antibody
    • ASXL1_HUMAN antibody
    • KIAA0978 antibody
    • Putative Polycomb group protein ASXL1 antibody
    see all

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プロトコール

参考文献

This product has been referenced in:
  • Balasubramani A  et al. Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1-BAP1 complex. Nat Commun 6:7307 (2015). WB ; Mouse . Read more (PubMed: 26095772) »

See 1 Publication for this product

レビューと Q&A

I have continued to look through our catalogue and I cannot find any kits that would allow you to conjugate an antibody to Protein A/G beads. I did however find this kit which may work: Please let me know if there is anything else I can h...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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