製品の概要

  • 製品名Anti-ASS1 antibody
    ASS1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ASS1
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow
  • 免疫原

    Recombinant protein fragment with a sequence corresponding to a region within amino acids 155 and 410 of Human ASS1 (NP_446464).

  • ポジティブ・コントロール
    • A431 cell lysate, mixed OVCA

法規制情報

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab95964 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 47 kDa.
IHC-P Use at an assay dependent concentration.

ターゲット情報

  • パスウェイAmino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3.
    Nitrogen metabolism; urea cycle; (N(omega)-L-arginino)succinate from L-aspartate and L-citrulline: step 1/1.
  • 関連疾患Defects in ASS1 are the cause of citrullinemia type 1 (CTLN1) [MIM:215700]. Citrullinemia belongs to the urea cycle disorders. It is an autosomal recessive disease characterized primarily by elevated serum and urine citrulline levels. Ammonia intoxication is another manifestation. CTLN1 usually manifests in the first few days of life. Affected infants appear normal at birth, but as ammonia builds up in the body they present symptoms such as lethargy, poor feeding, vomiting, seizures and loss of consciousness. Less commonly, a milder CTLN1 form can develop later in childhood or adulthood.
  • 配列類似性Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Argininosuccinate synthase 1 antibody
    • Argininosuccinate synthase antibody
    • Argininosuccinate synthetase 1 antibody
    • ASS antibody
    • Ass-1 antibody
    • ass1 antibody
    • ASSA antibody
    • ASSY_HUMAN antibody
    • Citrulline aspartate ligase antibody
    • Citrulline--aspartate ligase antibody
    • CTLN1 antibody
    see all

Anti-ASS1 antibody 画像

  • Anti-ASS1 antibody (ab95964) at 1/500 dilution + A431 whole cell lysate at 30 µg

    Predicted band size : 47 kDa
  • ab95964, at 1/100, staining paraffin-embedded mixed OVCA by Immunohistochemistry.

Anti-ASS1 antibody (ab95964) 使用論文

ab95964 has not yet been referenced specifically in any publications.

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Tissue section if human kidney or liver can be used as positive control for ASS1.

Kidney:

http://www.abcam.com/ab4347: Kidney (human) normal tissue slides
...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"