製品の概要

  • 製品名Anti-ASPA antibody
    ASPA 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to ASPA
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Rat
  • 免疫原

    Synthetic peptide:

    TLSAKSIRSTLH

    by a Cysteine residue linker, corresponding to C terminal amino acids 301-312 of Mouse ASPA (NP_075602.2).

  • ポジティブ・コントロール
    • Mouse and Rat kidney lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab112530 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.01 - 0.03 µg/ml. Detects a band of approximately 35 kDa (predicted molecular weight: 35 kDa). For 1 hour.

ターゲット情報

  • 機能Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it act as a scavenger of NAA from body fluids.
  • 組織特異性Brain white matter, skeletal muscle, kidney, adrenal glands, lung and liver.
  • 関連疾患Defects in ASPA are the cause of Canavan disease (CAND) [MIM:271900]; also known as spongy degeneration of the brain. CAND is a rare neurodegenerative condition of infancy or childhood characterized by white matter vacuolization and demeylination that gives rise to a spongy appearance. The clinical features are onset in early infancy, atonia of neck muscles, hypotonia, hyperextension of legs and flexion of arms, blindness, severe mental defect, megalocephaly, and death by 18 months on the average.
  • 配列類似性Belongs to the AspA/AstE family. Aspartoacylase subfamily.
  • 細胞内局在Cytoplasm. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ACY 2 antibody
    • ACY-2 antibody
    • ACY2 antibody
    • ACY2_HUMAN antibody
    • Aminoacylase 2 antibody
    • Aminoacylase-2 antibody
    • Aminoacylase2 antibody
    • ASP antibody
    • ASPA antibody
    • Aspartoacylase (aminoacylase 2, Canavan disease) antibody
    • Aspartoacylase (Canavan disease) antibody
    • Aspartoacylase antibody
    • NUR 7 antibody
    • NUR7 antibody
    • OTTMUSP00000006437 antibody
    • RP23-213I10.1 antibody
    • Small lethargic antibody
    see all

Anti-ASPA antibody 画像

  • Anti-ASPA antibody (ab112530) at 0.01 µg/ml + Mouse Kidney lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 35 kDa

Anti-ASPA antibody (ab112530) 使用論文

ab112530 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"