製品の概要

  • 製品名Anti-ASNA1 antibody
    ASNA1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ASNA1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Zebrafish
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 45-249 of Human ASNA1.

  • ポジティブ・コントロール
    • HCT116 cells lysate

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab96388 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 39 kDa.

ターゲット情報

  • 機能ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting (By similarity). May be involved in insulin signaling.
  • 組織特異性Expressed in the epithelial cells of the liver, kidney, and stomach wall, in the adrenal medulla, in the islet cells of the pancreas, in the red pulp of the spleen, and in cardiac and skeletal muscle.
  • 配列類似性Belongs to the arsA ATPase family.
  • 細胞内局在Cytoplasm. Endoplasmic reticulum. Nucleus > nucleolus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ARSA 1 antibody
    • ARSA antibody
    • ArsA arsenite transporter ATP binding homolog 1 antibody
    • ArsA arsenite transporter, ATP binding, E. coli, homolog of, 1 antibody
    • ArsA arsenite transporter, ATP-binding, homolog 1 (bacterial) antibody
    • ARSA I antibody
    • ARSA-I antibody
    • ARSA1 antibody
    • ARSAI antibody
    • Arsenical pump driving ATPase antibody
    • Arsenical pump-driving ATPase antibody
    • Arsenical resistance ATPase antibody
    • Arsenite translocating ATPase antibody
    • Arsenite transporting ATPase antibody
    • Arsenite-stimulated ATPase antibody
    • ASNA 1 antibody
    • ASNA I antibody
    • ASNA-I antibody
    • ASNA_HUMAN antibody
    • ASNA1 antibody
    • Asna1 protein antibody
    • ASNAI antibody
    • ATPase ASNA1 antibody
    • GET3 antibody
    • Golgi to ER traffic 3 homolog antibody
    • hARSA-I antibody
    • hASNA-I antibody
    • MGC3821 antibody
    • Transmembrane domain recognition complex 40 kDa ATPase subunit antibody
    • Transmembrane domain recognition complex, 40kDa antibody
    • TRC40 antibody
    see all

Anti-ASNA1 antibody 画像

  • Anti-ASNA1 antibody (ab96388) at 1/1000 dilution + HCT116 whole cell lysate at 30 µg

    Predicted band size : 39 kDa

Anti-ASNA1 antibody (ab96388) 使用論文

ab96388 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab96388.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"