製品の概要

  • 製品名Anti-ASK1 (phospho S966) antibody
    ASK1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ASK1 (phospho S966)
  • 特異性ab39402 detects endogenous levels of ASK1 only when phosphorylated at Serine 966.
  • アプリケーション適用あり: ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic phosphopeptide: SISpLP, derived from Human ASK1 around the phosphorylation site of Serine 966

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS, 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab39402 was affinity purified from rabbit antiserum by affinity chromatography using epitope specific phosphopeptide. The antibody against non phosphopeptide was removed by chromatography using non phosphopeptide corresponding to the phosphorylation site.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab39402 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/20000.
IHC-P Use at an assay dependent concentration.

ターゲット情報

  • 機能Component of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death.
  • 組織特異性Abundantly expressed in heart and pancreas.
  • 配列類似性Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
    Contains 1 protein kinase domain.
  • 翻訳後修飾Dephosphorylated and activated by PGAM5.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Apoptosis signal regulating kinase 1 antibody
    • Apoptosis signal-regulating kinase 1 antibody
    • ASK 1 antibody
    • ASK-1 antibody
    • ASK1 antibody
    • M3K5 antibody
    • M3K5_HUMAN antibody
    • MAP/ERK kinase kinase 5 antibody
    • MAP3K5 antibody
    • MAPK/ERK kinase kinase 5 antibody
    • MAPKKK5 antibody
    • MEK kinase 5 antibody
    • MEKK 5 antibody
    • MEKK5 antibody
    • Mitogen activated protein kinase kinase kinase 5 antibody
    • Mitogen-activated protein kinase kinase kinase 5 antibody
    see all

Anti-ASK1 (phospho S966) antibody 画像

  • ab39402, at a 1/100 dilution, staining human ASK1 in breast carcinoma tissue by Immunohistochemistry, Paraffin embedded tissue.
  • ab39402, at a 1/100 dilution, staining human ASK1 in breast carcinoma tissue (treated with synthesized phosphopeptide) by Immunohistochemistry, Paraffin embedded tissue.

Anti-ASK1 (phospho S966) antibody (ab39402) 使用論文

ab39402 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"