The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/2000. Predicted molecular weight: 24 kDa.
Asf1 (anti silencing function 1) belongs to the H3/H4 family of histone chaperones. Its function has not been fully elucidated but it is believed to be involved in ensuring a constant supply of histones at sites of nucleosome assembly. Asf1 interacts with the DNA damage checkpoint protein Rad53 and so may have a role in cell cycle regulation and DNA responses. ASF1 A and B (the two human subtypes) are the only known substrate for Tousled like kinase (TLK).
Anti silencing factor 1 antibody
anti-silencing function 1A antibody
anti-silencing function 1B antibody
ASF1 anti-silencing function 1 homolog A antibody
ASF1 anti-silencing function 1 homolog B antibody
Western blot - ASF1 alpha/beta antibody (ab53608)
All lanes : Anti-ASF1 A+B antibody (ab53608) at 1/2000 dilution
Lane 1 : Drosophila embryo lysate Lane 2 : Drosophila embryo lysate Lane 3 : Drosophila embryo lysate
Lario LD et al. ANTI-SILENCING FUNCTION1 proteins are involved in ultraviolet-induced DNA damage repair and are cell cycle regulated by E2F transcription factors in Arabidopsis. Plant Physiol162:1164-77 (2013).
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