製品の概要

  • 製品名Anti-ASAH1 antibody [1A7]
    ASAH1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [1A7] to ASAH1
  • アプリケーション適用あり: WB, IHC-P, Sandwich ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 25-125 of Human ASAH1 (NP_808592) with a 26 kDa proprietary tag.

  • ポジティブ・コントロール
    • IHC-P: Human heart and prostate tissues WB: ASAH1 transfected 293T cell lysate; recombinant ASAH1 protein

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーpH: 7.40
    Constituent: PBS
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノモノクローナル
  • クローン名1A7
  • アイソタイプIgG3
  • 軽鎖の種類kappa
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab124262 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 45 kDa.
IHC-P Use a concentration of 5 µg/ml.
Sandwich ELISA Use at an assay dependent dilution.

ターゲット情報

  • 機能Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
  • 組織特異性Broadly expressed with highest expression in heart.
  • 関連疾患Defects in ASAH1 are the cause of Farber lipogranulomatosis (FL) [MIM:228000]; also known as Farber disease (FD). This sphingolipid disease is characterized by subcutaneous lipid-loaded nodules, excruciating pain in the joints and extremities, marked accumulation of ceramide in lysosomes, and death by three years of age.
  • 配列類似性Belongs to the acid ceramidase family.
  • 細胞内局在Lysosome.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AC antibody
    • ACDase antibody
    • Acid CDase antibody
    • Acid ceramidase antibody
    • Acid ceramidase precursor antibody
    • Acid ceramidase subunit beta antibody
    • Acylsphingosine deacylase antibody
    • ASAH 1 antibody
    • ASAH antibody
    • ASAH1 antibody
    • ASAH1_HUMAN antibody
    • FLJ21558 antibody
    • FLJ22079 antibody
    • N acylsphingosine amidohydrolase (acid ceramidase) 1 antibody
    • N acylsphingosine amidohydrolase 1 antibody
    • N acylsphingosine amidohydrolase antibody
    • N-acylsphingosine amidohydrolase antibody
    • N-acylsphingosine deacylase antibody
    • PHP antibody
    • PHP32 antibody
    • Putative 32 kDa heart protein antibody
    • SMAPME antibody
    see all

Anti-ASAH1 antibody [1A7] 画像

  • ab124262, at 5 µg/ml, staining ASAH1 in formalin fixed, paraffin embedded Human heart tissue by Imunohistochemistry.
  • ab124262, at 5 µg/ml, staining ASAH1 in formalin fixed, paraffin embedded Human prostate tissue by Imunohistochemistry.
  • All lanes : Anti-ASAH1 antibody [1A7] (ab124262) at 1/500 dilution

    Lane 1 : ASAH1 transfected 293T lysate
    Lane 2 : Non-transfected 293T lysate


    Predicted band size : 45 kDa
  • ab124262, detecting recombinant tagged ASAH1 protein by ELISA. Detection limit is approximately 1 ng/ml as a capture antibody.

Anti-ASAH1 antibody [1A7] (ab124262) 使用論文

ab124262 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"