製品の概要

  • 製品名Anti-ARPC2 antibody
    ARPC2 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to ARPC2
  • 特異性This antibody is expected to recognise both reported isoforms as represented by NP_005722 and NP_690601.
  • アプリケーション適用あり: IHC-P, WB, ICC/IFmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat, Zebrafish
  • 免疫原

    Synthetic peptide: EMKTITGKTFSSR, corresponding to amino acids 288-300 of Human ARPC2.

  • ポジティブ・コントロール
    • Hela and Human Muscle lysates.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab11798 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 3 - 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
WB Use a concentration of 0.1 - 0.5 µg/ml. Detects a band of approximately 34 kDa.Can be blocked with Human ARPC2 peptide (ab23207).
ICC/IF Use at an assay dependent concentration. PubMed: 22021442

ターゲット情報

  • 機能Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
  • 配列類似性Belongs to the ARPC2 family.
  • 細胞内局在Cytoplasm > cytoskeleton. Cell projection.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Actin related protein 2/3 complex subunit 2 34kDa antibody
    • Actin related protein 2/3 complex subunit 2 antibody
    • Actin-related protein 2/3 complex subunit 2 antibody
    • ARC 34 antibody
    • ARC34 antibody
    • Arp2/3 complex 34 kDa subunit antibody
    • ARP2/3 protein compex subunit 34 antibody
    • ARPC 2 antibody
    • Arpc2 antibody
    • ARPC2_HUMAN antibody
    • p34 Arc antibody
    • p34-ARC antibody
    • p34Arc antibody
    • PNAS 139 antibody
    • PNAS139 antibody
    • PRO 2446 antibody
    • PRO2446 antibody
    see all

Anti-ARPC2 antibody 画像

  • ab11798 (3.8 µg/ml) staining ARPC2 in paraffin-embedded Human spleen tissue following steamed antigen retrieval with citrate buffer (pH6).

Anti-ARPC2 antibody (ab11798) 使用論文

This product has been referenced in:
  • Xia P  et al. WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner. J Exp Med 211:2119-34 (2014). Read more (PubMed: 25225459) »
  • Chauhan BK  et al. Balanced Rac1 and RhoA activities regulate cell shape and drive invagination morphogenesis in epithelia. Proc Natl Acad Sci U S A 108:18289-94 (2011). ICC/IF ; Mouse . Read more (PubMed: 22021442) »

See all 3 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"