製品の概要

  • 製品名Anti-Arp2 antibody [FMS96]
    Arp2 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [FMS96] to Arp2
  • 特異性This antibody recognizes Arp2 (approx. 40-45 kDa).
  • アプリケーション適用あり: Indirect ELISA, ICC/IF, WBmore details
  • 種交差性
    交差種: Mouse, Rat, Dog, Human
  • 免疫原

    Recombinant full length protein (Human)

  • ポジティブ・コントロール
    • Total cell extract of C2 mouse myoblast cells.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab49674 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Indirect ELISA Use at an assay dependent dilution.
ICC/IF Use a concentration of 10 µg/ml.
WB Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 40-45 kDa (predicted molecular weight: 45 kDa).

ターゲット情報

  • 機能Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament.
  • 配列類似性Belongs to the actin family. ARP2 subfamily.
  • 細胞内局在Cytoplasm > cytoskeleton. Cell projection.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Actin like protein 2 antibody
    • Actin related protein 2 antibody
    • Actin-like protein 2 antibody
    • Actin-related protein 2 antibody
    • ACTR2 antibody
    • ARP2 actin related protein 2 homolog (yeast) antibody
    • ARP2 antibody
    • ARP2/3 COMPLEX antibody
    • ARP2_HUMAN antibody
    • OTTHUMP00000159937 antibody
    • OTTHUMP00000202270 antibody
    see all

Anti-Arp2 antibody [FMS96] 画像

  • C2C12 cells were incubated with ab49674 at 10 µg/ml followed by Goat Anti Mouse IgG Alexa-488 (green staining). The red staining is obtained by staining actin with Alexa-546 phalloidin.
  • Immunofluorescence analysis of dendritic cells infected with HIV, staining Arp2 (blue) with ab49674 at 5 mg/ml.

Anti-Arp2 antibody [FMS96] (ab49674) 使用論文

This product has been referenced in:
  • Wang F  et al. Arp2/3 complex inhibition prevents meiotic maturation in porcine oocytes. PLoS One 9:e87700 (2014). ICC/IF ; Pig . Read more (PubMed: 24498171) »
  • Naj X  et al. The formins FMNL1 and mDia1 regulate coiling phagocytosis of Borrelia burgdorferi by primary human macrophages. Infect Immun 81:1683-95 (2013). Human . Read more (PubMed: 23460512) »

See all 6 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"