製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to ARNTL2
  • アプリケーション
    適用あり: IHC-P, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chicken, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within the N terminal amino acids 36-85 (TAMGSFSSHM TEFPRKRKGS DSDPSQSGIM TEKVVEKLSQ NPLTYLLSTR) of human ARNTL2 (NP_064568).

  • ポジティブ・コントロール
    • MCF7 cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab86530 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 5 µg/ml.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 71 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 関連性
    ARNTL2 (aryl hydrocarbon receptor nuclear translocator-like 2) is a basic Helix-Loop-Helix-Per-Arnt-Sim (bHLH-PAS) transcription factor. ARNTL2-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription. Also, in umbilical vein endothelial cells, ARNTL2 activates SERPINE1 through E-box sites. This transactivation is inhibited by PER2 and CRY1. It may participate in circadian clock regulation.
  • 細胞内局在
    Nuclear
  • 参照データベース
  • 別名
    • ARNT L2 antibody
    • ARNTL 2 antibody
    • ARNTL2 antibody
    • ARNTL2 protein antibody
    • Aryl hydrocarbon receptor nuclear translocator like 2 antibody
    • Aryl hydrocarbon receptor nuclear translocator like protein 2 antibody
    • Aryl hydrocarbon receptor nuclear translocator-like 2 antibody
    • Basic helix loop helix PAS protein MOP9 antibody
    • Basic-helix-loop-helix-PAS protein MOP9 antibody
    • bHLHe6 antibody
    • BMA L2 antibody
    • BMAL 2 antibody
    • BMAL2 antibody
    • Brain and muscle ARNT like 2 antibody
    • Brain and muscle ARNT-like 2 antibody
    • CLIF antibody
    • CYCLE like factor antibody
    • CYCLE-like factor antibody
    • Member of PAS protein 9 antibody
    • MGC124257 antibody
    • MGC149671 antibody
    • MGC149672 antibody
    • MGC158186 antibody
    • MOP 9 antibody
    • MOP9 antibody
    • PASD 9 antibody
    • PASD9 antibody
    • Transcription factor BMAL 2 antibody
    • Transcription factor BMAL2 antibody
    • wu:fj90c09 antibody
    see all

画像

  • Anti-ARNTL2 antibody (ab86530) at 1 µg/ml (in 5% skim milk / PBS buffer) + MCF7 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 71 kDa
    Observed band size : ~65 kDa (why is the actual band size different from the predicted?)
    Gel concentration: 12%
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human placenta tissue labelling ARNTL2 with ab86530 at 5µg/ml.

参考文献

This product has been referenced in:
  • Lebailly B  et al. Linking the circadian rhythm gene Arntl2 to interleukin 21 expression in type 1 diabetes. Diabetes 63:2148-57 (2014). Read more (PubMed: 24520124) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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