The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 20 µg/ml.
Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 27 kDa (predicted molecular weight: 23 kDa).
Use at an assay dependent concentration.
機能May be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation.
組織特異性Expressed in all hematopoietic cell lineages, but the highest level of expression is found in early myeloid progenitor cells. Expressed in brain, bone marrow, thymus and lung. Expressed at low level in liver, kidney and spleen. Not detected in heart.
配列類似性Belongs to the ARL6ip family.
発生段階Down-regulated during myeloid differentiation.
細胞内局在Endomembrane system. Predominantly localized to intracytoplasmic membranes.