製品の概要

  • 製品名Anti-ARL2 antibody - N-terminal
    ARL2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ARL2 - N-terminal
  • アプリケーション適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Human
  • ポジティブ・コントロール
    • Hela cell line lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度Protein G purified
  • 特記事項(精製)ab71288 is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab71288 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 21 kDa (predicted molecular weight: 21 kDa).

ターゲット情報

  • 機能Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassembly of the apical junction complexes. Antagonizes the effect of TBCD on epithelial cell detachment and tight and adherens junctions disassembly. Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. Component of a regulated secretory pathway involved in Ca(2+)-dependent release of acetylcholine. Required for normal progress through the cell cycle.
  • 配列類似性Belongs to the small GTPase superfamily. Arf family.
  • 翻訳後修飾Not N-myristoylated.
  • 細胞内局在Mitochondrion intermembrane space. Cytoplasm > cytoskeleton > centrosome. Nucleus. Cytoplasm. The complex formed with ARL2BP, ARL2 and SLC25A6 is expressed in mitochondria. The complex formed with ARL2BP, ARL2 and SLC25A4 is expressed in mitochondria (By similarity). Not detected in the Golgi, nucleus and on the mitotic spindle. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ADP ribosylation factor like 2 antibody
    • ADP-ribosylation factor-like protein 2 antibody
    • ARFL2 antibody
    • Arl184 antibody
    • Arl2 antibody
    • ARL2_HUMAN antibody
    see all

Anti-ARL2 antibody - N-terminal 画像

  • Anti-ARL2 antibody - N-terminal (ab71288) at 1/100 dilution + Hela cell line lysate at 35 µg/ml

    Predicted band size : 21 kDa
    Observed band size : 21 kDa
    Additional bands at : 32 kDa,56 kDa. We are unsure as to the identity of these extra bands.

Anti-ARL2 antibody - N-terminal (ab71288) 使用論文

This product has been referenced in:
  • Price HP  et al. The small GTPase ARL2 is required for cytokinesis in Trypanosoma brucei. Mol Biochem Parasitol 173:123-31 (2010). Read more (PubMed: 20653091) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"